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overview Walter L. Palmer Distinguished Service Professor of Medicine and Pediatrics Dean for Translational Medicine Director, Institute for Translational Medicine I am Dean for Translational Medicine and founding Director of the Institute for Translational Medicine, home of the University of Chicago-Rush University NIH/NCATS CTSA award. I have served the CTSA Consortium as a co-Chair, Steering Committee member, and co-Chair of the Strategic Goal 3 and Collaboration/Engagement Domain Task Force. My research programs primarily address asthma. I have extensive experience studying airway smooth muscle (ASM) function and dysfunction in asthma, having studied smooth muscle specific gene transcription, protein accumulation, and hypertrophy, and signaling mechanisms that regulate these; ASM contraction and its reversal, and the mechanisms that regulate these; and ASM mediated-airway narrowing, airway constrictor responsiveness, and lung function in both animal models and humans. Additional studies address asthma genetics and therapeutics in mechanistic and therapeutic clinical studies and preclinical development of novel asthma treatments. Recently, I have focused on the inhibition of pulmonary fibrosis and on the inhibition of breast cancer metastasis using novel small molecules discovered in our asthma studies. I directed the University of Chicago's NHLBI-sponsored T32 Research Training Program in Respiratory Biology for 25 years, led or co-led two NHLBI Multidisciplinary K12 Training Programs, co-led an NIH Broadening Experiences in Scientific Training (BEST) award, and currently lead a Burroughs Wellcome Fund Physician Scientist Institutional Award. My ORCID is 0000-0002-0898-8530. My Scopus ID is 7006796752. My NIH COMMONS name is jsolway. BS 1974 Massachusetts Institute of Technology (Electrical Engineering) MD cum laude 1978 Harvard University (Medicine) Residency 1981 Brigham and Women's Hospital (Internal Medicine) Fellowship 1983 Harvard Medical School (Pulmonary Medicine)
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